Table 2 Lesion count (sensitivity in %) MRI scoring.

From: Artificial double inversion recovery images can substitute conventionally acquired images: an MRI-histology study

Histology

MRI rating

Lesion type

N

Blinded

Unblinded

Blinded

Unblinded

Blinded

Unblinded

Blinded

Unblinded

Conventional DIR

Conventional DIR retro

DIR from 3D-T1 + PD/T2 pro

DIR from 3D-T1 + PD/T2 retro

DIR from 3D-T1 + FLAIR pro

DIR from 3D-T1 + FLAIR retro

3D-T1 pro

3D-T1 retro

Type I

6

5 (83.3)

5 (83.3)

4 (75.0)

5 (83.3)

5 (83.3)

5 (83.3)

4 (75.0)

5 (83.3)

Type II

47

0 (0.0)

3 (6.4)

0 (0)

2 (4.3)

0 (0.0)

2 (4.3)

0 (0.0)

3 (6.4)

Type III

76

12 (15.8)

51 (67.1)

6 (7.9)

32 (42.1)

7 (9.2)

42 (55.3)

3 (3.9)

31 (40.8)

Type IV

13

8 (61.5)

11 (84.6)

9 (69.2)

11 (84.6)

8 (61.5)

10 (76.9)

8 (61.5)

10 (76.9)

Type I-IV

142

25 (17.6)

70 (49.3)

19 (13.4)

50 (35.2)*

20 (14.1)

59 (41.5)

15 (10.6)

49 (34.5)*

WML

7

6 (85.7)

6 (85.7)

7 (100)

7 (100)

6 (85.7)

6 (85.7)

7 (100)

7 (100)

Total

149

31

76

26

57

26

65

22

46

  1. N = number of detected/discernible cortical lesions; WML = white matter lesion.
  2. *Significant differences (i.e. P < 0.05) compared to conventional DIR.
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