Figure 2 | Scientific Reports

Figure 2

From: Transcriptomes of electrophysiologically recorded Dbx1-derived respiratory neurons of the preBötzinger complex in neonatal mice

Figure 2

Transcriptomic differences in Type-1 and Type-2 neurons. (A) L2FC versus adjusted p values of 31,543 genes computed using DESeq2. Genes upregulated in Type-1 are in magenta and those upregulated in Type-2 are in blue-cyan. Gray shaded area represents the region expanded in (Aa), which corresponds to L2FC > 1.5 and padj < 0.01. (B) Bar chart (top) shows PCs (x-axis) and variability (y-axis) in the expression of 123 DE genes. Scatter plot (bottom) shows clustering of Type-1 (magenta) and Type-2 (blue-cyan) neurons using the first two PCs (highlighted in dark violet at top). The gray dashed line shows the boundary between the clusters of Type-1 and Type-2 neurons drawn by LDA.

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