Figure 6
(a) Histopatholology scores of tarsal inflammation and bone destruction confirm disease in CIA mice, and show a significant reduction with prednisolone treatment. (b–d) Representative hematoxylin and eosin-stained images for each group are shown here with × 50 magnification. Black arrows indicate pannus causing bone erosion in the navicular (1), talus (2) and distal tibia (3). Yellow arrows indicate inflammation. The prednisolone-treated group has less inflammation (yellow arrows), and less bone erosion (black arrows; mainly in the navicular bone, while talus and distal tibia are less affected).
