Figure 5

Effect of AEPAS on PI3K, AKT, Bcl2, and PCNA in the liver and pancreas of diabetic rats. AEPAS: aqueous extract of P. americana seeds; PCNA: proliferating cell nuclear antigen; CT: control group; DC: diabetic control; DM: diabetic + metformin group; PA-1: P. americana treated group (26.7 mg/kg); PA-2: P. americana treated group (53.3 mg/kg) PA-3: P. americana treated group (106.6 mg/kg).