Table 1 Characteristics of primary and secondary MN patients at the time of renal biopsy and treatment response.
Characteristics | Primary | Secondary |
|---|---|---|
Number of patients | 69 | 35 |
Male; number (%) | 40 (58.0) | 16 (45.7) |
Age, years; mean | 60.2 ± 13.6 | 52.0 ± 15.8* |
Proteinuria (g/day) | 3.7 ± 2.5 | 2.5 ± 1.8#1* |
Serum creatinine (mg/dl) | 0.9 ± 0.3 | 0.8 ± 0.5 |
Serum albumin (g/dl) | 2.6 ± 0.8 | 2.9 ± 0.7* |
% of IgG4 positivity by IHC | 59.4* | 5.7 |
Immunosuppressive therapy number (%) | ||
Prednisolone | 31 (44.9) | 10 (28.6) |
Prednisolone + Cyclosporine | 13 (19.4) | 0 |
Prednisolone + Azathioprine | 1 (1.5) | 1 (2.7) |
Prednisolone + Cyclophosphamide | 0 | 1 (2.7) |
Prednisolone + Mizoribine | 1 (1.5) | 1 (2.7) |
Prednisolone + Tacrolimus | 0 | 1 (2.7) |
Prednisolone + Mycophenolate mofetil | 0 | 3 (8.1) |
Total number (%) | 46 (66.7) | 17 (48.6) |
Clinical course | ||
6Â months | ||
 Proteinuria (g/day) | 1.9 ± 2.7 | 2.5 ± 3.3 |
 Serum creatinine (mg/dl) | 1.0 ± 0.5 | 0.8 ± 0.3 |
 Serum albumin (g/dl) | 3.3 ± 0.8 | 3.2 ± 0.7 |
 % of complete remission (number) | 24.5 (12) | 33.3 (6) |
 % of composite remission (number) | 57.1 (28) | 61.1 (11) |
1Â year | ||
 Proteinuria (g/day) | 1.5 ± 2.4 | 1.6 ± 2.6 |
 Serum creatinine (mg/dl) | 1.1 ± 0.9 | 0.9 ± 0.4 |
 Serum albumin (g/dl) | 3.5 ± 0.8 | 3.5 ± 0.8 |
 % of complete remission (number) | 44.9 (22) | 47.1 (8) |
 % of composite remission (number) | 67.3 (33) | 76.5 (13) |
