Table 4 Clinical information in each case of Ext1/Ext2–associated MN.

Case	Clinical diagnosis	Age	Sex	Proteinuria (g/day)	Serum creatinine (mg/dl)	Serum albumin (g/dl)	Complications	ANA/dsDNA/others	C3/C4/CH50	IHC of IgG4	Immunosuppressive therapy
1	Primary	55	Female	0.8	0.53	2.9	None	neg/NA/NA	Normal	neg	None
2	Primary	63	Male	2.1	1.00	3.2	None	neg/NA/NA	Normal	pos	Prednisolone + Cyclosporine
3	Primary	62	Female	1.3	0.48	2.5	None	neg/NA/NA	Normal	neg	Prednisolone
4	Primary	59	Male	2.5	1.16	4.3	None	neg/NA/NA	Normal	neg	None
5	Primary	53	Male	1.1	1.35	4.0	None	NA/NA/NA	NA	neg	Prednisolone
6	Primary	49	Male	0.6	0.73	3.8	None	320/neg/neg	Normal	neg	None
7	Primary	29	Female	6.1	0.51	2.0	None	320/neg/neg	Normal	pos	Prednisolone
8	Primary ^#1	49	Male	2.1	0.68	3.0	None	neg/neg/neg	Normal	pos	Prednisolone
9	Primary^#2	69	Female	8.2	1.07	1.5	None	neg/NA/NA	Normal	pos	Prednisolone + Cyclosporine
10	Secondary	25	Male	0.2	0.70	4.3	Hepatitis B	neg/NA/NA	Normal	neg	None
11	Secondary	37	Male	1.5	0.68	2.2	Hepatitis B	neg/NA/NA	Normal	neg	Interferon
12	Secondary	65	Male	6.7	0.95	1.7	Prostate cancer Ulcerative colitis Guillain–Barre syndrome	neg/neg/neg	Normal	neg	Prednisolone
13	Secondary	35	Female	3.3	0.58	2.2	Thyroiditis	1280/neg/neg	Normal	neg	Prednisolone
14	Secondary	67	Male	2.1	0.83	3.5	Lung cancer	neg/NA/NA	Normal	neg	None
15	Secondary	46	Male	1.2	0.80	3.5	Lupus	320/neg/RNP, ssDNA,SS-A	33/9/ < 10	neg	Prednisolone + Tacrolimus
16	Secondary	59	Female	1.8	0.72	2.7	Lupus + scleroderma	640/neg/ssDNA	34/14/5	neg	Prednisolone + Mycophenolate mofetil
17	Secondary	52	Male	0.5	0.50	4.0	Lupus	1280/neg/ssDNA	Normal	neg	Prednisolone

ANA antinuclear antibody, neg negative, pos positive, NA not available, ssDNA single strand DNA, dsDNA double strand DNA, #1 enhanced staining of PLA2R was also found, #2 enhanced staining of THSD7A was also found.

Quick links

Search