Table 2 EcmiRNAs NGS data.

From: Extracellular circulating miRNAs as stress-related signature to search and rescue dogs

Name

T1 vs T0

Max group means*

Fold change

Log2 fold change

P-value

FDR** p-value

− log10 FDR

p-value

Bonferroni

cfa-let-7f

3625.500

1.509

0.593

0.000002

0.000493

3.306839

0.000493

cfa-let-7a

7115.167

1.367

0.451

0.000253

0.032198

1.492165

0.054397

  1. Data were filtered with max group means higher than 10, an FDR-p-value less than 0.05, and a standard p-value (significance at < 0.05). Differential expression analysis of serum miRNome at T1 vs T0 revealed that cfa-let-7f (FDR p-value < 0.001 applying Bonferroni correction for multiple tests 0.000493) and cfa-let-7 (FDR p-value < 0.05 applying Bonferroni correction for multiple tests 0.054397) were significantly upregulated.
  2. *Max group means is the maximum of the average RPKM's (Reads Per Kilobase of transcript, per Million mapped reads).
  3. **False discovery rate corrected p-value is the expected proportion of false-positive genes in a set of genes.
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