Figure 4

Relationship between I.I._com and circulating naïve and memory CD4+ T-cell abundances before and after probiotic supplement. (A) Representative flow cytometry profiles showing the gating strategy for the naïve and memory CD4 T-cells. Naïve and memory CD4+ T-cells were respectively defined as CD45RA+/CD45RO− and CD45RA−/CD45RO+. (B) Relationship between percent change in I.I._com post- versus pre-supplement plotted against the percent change in CD4+ CD45RO+ T-cells post- versus pre-supplement (Pearson’s correlation = 0.51, p = 0.061). (C) Relationship between percent change in I.I._com post- versus pre-supplement plotted against the percent change in CD4+ CD45RA+ T-cells post- versus pre-supplement Pearson’s correlation =  − 0.50, p = 0.060. (D) Relationship between percent change in I.I._com post- versus pre-supplement plotted against the percent change in CD4+ CD45RO+: CD4+ CD45RA+ T-cell ratio post- versus pre-supplement.