Table 1 On univariate analysis, both averages of the 10 min' and 20 min' detections were significant.

From: Interpretation of intraoperative parathyroid hormone monitoring according to the Rome criterion in primary hyperparathyroidism

Variable

Cure

Persistence

Total

OR (IC95%)

p value

Univariate analysis

Age (mean)

57

58

  

0.6

Sex

M

38

6

44

3.45 (0.90–12.77)

0.03623

F

154

7

161

Total

192

13

205

Baseline PTH

183.3

189.3

  

0.8054

PTH T10’

62.65

91.3

  

0.00059

PTH T20’

29.34

91.0

  

8.518e−07

< 0.0001

Technique

Bilateral exploration

139

12

151

 

0.2839

MIVAP

28

0

28

Focused

25

1

26

Total

192

13

205

Histology

1

37

5

42

 

0.4188

2

136

8

144

3

11

0

11

4

8

0

8

Total

192

13

205

US

Localized

184

1

185

249.8 (31.7–10,788.6)

1.901e−13

< 0.001

Not localized

8

12

20

Total

192

13

205

Scintigraphy

Localized

157

4

161

9.93 (2.59–46.7)

0.0001701

Not localized

35

9

44

Total

192

13

205

US + scintigraphy

Confirmed

154

1

155

47.5 (6.7–2067.4)

1.559e−07

< 0.0001

Not confirmed

38

12

50

Total

192

13

205

Localization

Cervical

171

5

176

 

7.829e−05

< 0.0001

Intrathyroid

17

7

24

Mediastinum

4

1

5

Total

192

13

205

  1. Equally significant was the difference between the number of patients in whom localization diagnostics (ultrasounds, scintigraphy) were effective, compared with cases with no localization. Patients with ectopic, intrathyroidal or mediastinal localizations had a significantly higher rate of persistence; finally, this rate was not significantly different according to histology.
  2. MIVAP minimally invasive video assisted parathyroidectomy, Histology 1 Hyperplasia, 2 adenoma, 3 atypical adenoma, 4 carcinoma; US ultrasounds.
  3. Significant values are in bold.