Table 1 All characteristics of risk factors, WHO targets and theoretical minimum risk exposure level.

From: Iran to achieve the SDG 3.4 at national and sub-national levels

Risk factor

Exposure definition

Data source

Related disease

WHO target for risk factors

Theoretical minimum risk exposure level (TMREL)

High systolic and diastolic blood pressure

Mean of systolic and diastolic blood pressure, measured in mmHg

STEPs surveys (from 2005 to 2009–2011–2016)

An additional studies: GCS1, IHHP2, MONICA3, NHS4,TLGS5

Rheumatic heart disease, Hypertensive heart disease, ischemic heart disease, ischemic stroke, hemorrhagic and other non-ischemic stroke, cardiomyopathy, myocarditis, endocarditis, atrial fibrillation and flutter, other circulatory diseases, chronic obstructive pulmonary disease, kidney disease

25% relative reduction in the prevalence of raised blood pressure

110–115 mm Hg

High FPG

Mean of serum fasting plasma glucose measured in mg/dl

STEPs surveys (from 2005 to 2009–2011–2016)

An additional studies: GCS, IHHP, MONICA, NHS,TLGS

Diabetes mellitus, Ischemic heart disease, Ischemic stroke, Hemorrhagic and other non-ischemic stroke, Kidney disease

Halt the rise in diabetes

4·8–5·4 mmol/L

Obesity and overweight

Mean of body mass index, measured in kg/m2

STEPs surveys (from 2005 to 2009–2011–2016)

An additional studies: an additional studies: GCS, IHHP, MONICA, NHS,TLGS

Colon and rectum cancers, liver cancer, pancreas cancer, breast cancer, corpus uteri cancer, ovary cancer, prostate cancer, non-hodgkin lymphoma, other lymphomas and multiple myeloma, leukemia, kidney cancer, gallbladder cancer, thyroid cancer, diabetes mellitus, hypertensive heart disease, ischemic heart disease, ischemic stroke, hemorrhagic and other non-ischemic stroke, kidney disease

Halt the rise in obesity

21–25 kg/m2

Physical inactivity

Average weekly physical activity at work, home, transport-related, and recreational measured by MET min per week

STEPs surveys ( from 2005 to 2009–2011–2016)

Colon and rectum cancers, breast cancer, diabetes mellitus, ischemic heart disease, ischemic stroke

10% reduction in the prevalence of physical inactivity

All adults experience 3000–4500 MET min per week

Smoking

Daily smoking

Smoking Impact ratio(SIR)

STEPs surveys (from 2005 to 2009–2011–2016)

Mouth and oropharynx cancers, esophagus cancer, stomach cancer, colon and rectum cancers, liver cancer, pancreas cancer

Trachea, bronchus and lung cancers, melanoma and other skin cancers, breast cancer, cervix uteri cancer, corpus uteri cancer, ovary cancer, prostate cancer, bladder cancer, non-hodgkin lymphoma, multiple myeloma, other lymphomas and multiple myeloma, leukemia, kidney cancer, gallbladder cancer, thyroid cancer, diabetes mellitus, rheumatic heart disease, hypertensive heart disease, ischemic heart disease, ischemic stroke, hemorrhagic and other non-ischemic stroke, chronic obstructive, pulmonary disease, asthma, other respiratory diseases

30% relative reduction in the prevalence of current tobacco use

All individuals are lifelong non-smokers

Salt intake

24 h urinary sodium measured in gram per day

Mean of salt intake

STEPs in 2016

Comprehensive project on household food pattern and nutritional status, TLGS, IHHP, Isfahan salt study, PGHHS6, Mashhad Study, YHHP7, Urban Health Equity assessment and Response Tool (Urban Heart-phase1), HIEs8

Direct : stomach cancer

Indirect : rheumatic heart disease, hypertensive heart disease, ischemic heart disease, ischemic stroke, hemorrhagic and other non-ischemic stroke, cardiomyopathy, myocarditis, endocarditis, atrial fibrillation and flutter, other circulatory diseases, chronic obstructive pulmonary disease, kidney disease

30% reduction in the mean population intake of salt

24 h urinary sodium between 1 and 5 g per day

  1. 1. Golestan Cohort Study.
  2. 2. Isfahan Healthy Heart Program.
  3. 3. Monitoring trends and determinants in cardiovascular disease.
  4. 4. National Health Survey.
  5. 5. The Tehran Lipid and Glucose Study.
  6. 6. Persian Gulf Healthy Heart Study.
  7. 7. Yazd Healthy Heart Program.
  8. 8. Household Income and Expenditure survey.