Table 2 The unadjusted association between baseline variables and 28-day mortality (n = 724).

From: The association between the non-HDL-cholesterol to HDL-cholesterol ratio and 28-day mortality in sepsis patients: a cohort study

Exposure

Statistics

Odds ratio (95% CI)

P value

Non-HDLc/HDL ratio

3.43 ± 2.01

1.10 (0.96, 1.27)

0.1682

Non-HDLc/HDL ratio tertile

Low

241 (33.29%)

Reference

 

Middle

241 (33.29%)

0.45 (0.19, 1.07)

0.0707

High

242 (33.43%)

1.06 (0.53, 2.11)

0.8707

Age (years) tertile

18–61

240 (33.15%)

Reference

 

62–74

238 (32.87%)

1.88 (0.85, 4.17)

0.1189

75–89

246 (33.98%)

1.49 (0.66, 3.39)

0.3380

Septic shock

No

302 (41.71%)

Reference

 

Yes

422 (58.29%)

1.10 (0.59, 2.07)

0.7653

Source of infection

Sepsis, pulmonary

312 (43.09%)

Reference

 

Sepsis, renal/UTI (including bladder)

163 (22.51%)

0.56 (0.24, 1.34)

0.1958

Sepsis, GI

71 (9.81%)

1.16 (0.45, 2.96)

0.7566

Sepsis, unknown

73 (10.08%)

1.13 (0.44, 2.87)

0.8050

Sepsis, cutaneous/soft tissue

58 (8.01%)

0.22 (0.03, 1.67)

0.1428

Sepsis, other

47 (6.49%)

a

0.9866

Gender

Male

390 (53.87%)

Reference

 

Female

334 (46.13%)

0.54 (0.28, 1.05)

0.0691

Ethnicity

Caucasian

518 (71.55%)

Reference

 

African American

90 (12.43%)

0.73 (0.25, 2.12)

0.5641

Hispanic

42 (5.80%)

0.79 (0.18, 3.40)

0.7468

Asian

11 (1.52%)

1.57 (0.19, 12.67)

0.6715

Native American

3 (0.41%)

a

0.9878

Other/Unknown

60 (8.29%)

1.43 (0.53, 3.82)

0.4782

Hospital discharge year

2014

335 (46.27%)

Reference

 

2015

389 (53.73%)

0.99 (0.53, 1.84)

0.9739

Admission weight, kg Tertile

27.21–70.2

237 (33.24%)

Reference

 

70.3–90.9

235 (32.96%)

1.15 (0.56, 2.37)

0.6960

91–227

241 (33.80%)

0.71 (0.32, 1.57)

0.3969

Temperature (°C) Tertile

30–36.38

220 (32.40%)

Reference

 

36.4–36.72

217 (31.96%)

0.28 (0.11, 0.72)

0.0082

36.8–41.8

242 (35.64%)

0.71 (0.36, 1.40)

0.3226

Respiratory rate (bpm) Tertile

4–27

227 (31.75%)

Reference

 

28–36

248 (34.69%)

1.50 (0.66, 3.37)

0.3301

37–60

240 (33.57%)

1.65 (0.74, 3.69)

0.2193

Heart rate (bpm) Tertile

26–103

224 (31.15%)

Reference

 

104–122

245 (34.08%)

1.20 (0.52, 2.79)

0.6736

123–201

250 (34.77%)

1.86 (0.85, 4.07)

0.1193

MAP (mmHg) Tertile

40–51

238 (33.10%)

Reference

 

52–71

240 (33.38%)

1.13 (0.55, 2.33)

0.7328

72–199

241 (33.52%)

0.71 (0.32, 1.58)

0.4031

Lactate level (mmol/L) Tertile

0.40–1.40

171 (32.95%)

Reference

 

1.50–2.40

171 (32.95%)

0.57 (0.22, 1.47)

0.2432

2.50–16.55

177 (34.10%)

1.69 (0.80, 3.57)

0.1707

SOFA score Tertile

0–0

152 (21.20%)

Reference

 

1–3

259 (36.12%)

9.28 (1.21, 70.97)

0.0318

4–15

306 (42.68%)

14.61 (1.97, 108.56)

0.0088

GCS score group

3–10

216 (30.51%)

Reference

 

11–14

207 (29.24%)

0.62 (0.28, 1.34)

0.2229

15–15

285 (40.25%)

0.53 (0.25, 1.10)

0.0871

APACHE IV score Tertile

13–60

212 (32.82%)

Reference

 

61–81

217 (33.59%)

3.31 (1.06, 10.33)

0.0389

82–164

217 (33.59%)

5.57 (1.88, 16.52)

0.0020

Acute Physiology Score III Tertile

4–47

213 (32.97%)

Reference

 

48–67

214 (33.13%)

1.83 (0.60, 5.54)

0.2876

68–147

219 (33.90%)

5.12 (1.92, 13.68)

0.0011

  1. Data are expressed as the mean ± SD, or percentage.
  2. BP blood pressure, GCS Glasgow Coma Scale, HDLc High-density lipoprotein cholesterol, LDLc Low-density lipoprotein cholesterol, MAP Mean Arterial Pressure, SOFA Sequential Organ Failure Assessment, UTI Urinary Tract Infection.
  3. aThe model failed because of the small sample size.
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