Table 2 Association of Ocular and Systemic Factors with 3D CVI (Whole Macula).

From: Three-dimensional modelling of the choroidal angioarchitecture in a multi-ethnic Asian population

 

Univariate

Multivariable

Estimate

Std. Error

P*

Estimate

Std. Error

P*

Ocular

2D CVI (Subfoveal), %

0.48

0.08

 < 0.001

0.41

0.09

 < 0.001

SFCT, µm

−2.19 × 10–5

2.65 × 10–3

0.993

SE, D

0.01

0.10

0.890

AL, mm

−0.23

0.20

0.253

IOP, mmHg

−0.03

0.07

0.619

MOPP, mmHG

−2.88 × 10–3

0.03

0.919

Systemic

Age, years

−0.04

0.03

0.207

−0.04

0.02

0.081

Gender, Female

−0.28

0.45

0.529

Ethnicity

Chinese

Reference

     

Indian

0.44

0.49

0.375

Malay

1.47

0.99

0.145

Hypertension

−0.04

0.47

0.941

Systolic BP, mmHg

−3.51 × 10–3

0.01

0.767

Diastolic BP, mmHg

−3.02 × 10–3

0.02

0.866

MAP, mmHg

−4.21 × 10–3

0.02

0.816

Anti-Hypertensive

0.54

0.61

0.382

Diabetes Mellitus

0.05

0.83

0.955

HbA1c, %

0.07

0.24

0.782

Blood Glucose, mmol/L

0.02

0.09

0.854

Hyperlipidaemia

−0.06

0.49

0.900

Total Cholesterol, mmol/L

−0.56

0.27

0.045

−0.08

0.23

0.715

HDL, mmol/L

−0.66

0.69

0.343

LDL, mmol/L

−0.40

0.28

0.160

BMI, kg/m2

0.08

0.06

0.200

Cardiovascular Disease

3.11

1.05

0.005

1.84

0.96

0.062

Chronic Kidney Disease

−0.92

1.60

0.566

Current Smoker

−0.33

0.69

0.634

  1. SFCT: subfoveal choroid thickness; Std. Error: standard error; 3D: three-dimensional; CVI: choroidal vascularity index; 2D: two-dimensional; SE: spherical equivalent: D: diopter; AL: axial length; IOP: intraocular pressure; MOPP: mean ocular perfusion pressure; BP: blood pressure; MAP: mean arterial pressure; HbA1c: glycated haemoglobin; HDL: high-density lipoprotein; LDL: low-density lipoprotein; BMI: body mass index.
  2. * Statistically significant associations (P < 0.05) are highlighted in bold.
  3. Model adjusted R-squared: 0.441; P < 0.001.