Figure 3 | Scientific Reports

Figure 3

From: Extrachromosomal DNA formation enables tumor immune escape potentially through regulating antigen presentation gene expression

Figure 3

ecDNA and tumor immune typing. (a) TME classification in tumors with and without ecDNA according to Thorsson et al. method. Chi-squared test P value is shown. C1: wound healing; C2: IFN-γ dominant; C3: inflammatory; C4: lymphocyte depleted; C5: immunologically quiet; C6: TGF-β dominant. (b) Immune type classification in tumors with ecDNA and without ecDNA according to Bagaev et al. method. Chi-squared test p value is shown. D immune-depleted; F fibrotic; IE immune-enriched, non-fibrotic; IE/F immune-enriched, fibrotic.

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