Table 2 Univariable and multivariable Cox regression analysis for progression-free survival.

From: Prognostic significance of platelet-to-albumin ratio in patients with esophageal squamous cell carcinoma receiving definitive radiotherapy

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Gender

Male/Female

0.983 (0.784–1.232)

0.879

  

Age

 ≤ 70/ > 70

1.046 (0.846–1.292)

0.679

  

Location

Cervical + Upper/Middle + Lower

1.155 (0.926–1.440)

0.202

  

T stage

T2-3/T4

1.335 (1.089–1.636)

0.005

0.683 (0.439–1.063)

0.091

N stage

N0/N + 

1.240 (0.973–1.581)

0.083

  

cTNM stage

II + III/IV

1.458 (1.188–1.788)

 < 0.001

2.147 (1.376–3.351)

 < 0.001

RT technique

2D-CRT/IMRT + 3D-CRT

0.877 (0.593–1.298)

0.512

  

Adjuvant chemotherapy

No/Yes

0.726 (0.586–0.898)

0.003

0.618 (0.493–0.774)

 < 0.001

Marrow depression

No/Yes

0.820 (0.670–1.005)

0.055

  

NLR

 < 2.62/ ≥ 2.62

1.352 (1.103–1.658)

0.004

1.103 (0.823–1.479)

0.513

PLR

 < 180/ ≥ 180

1.529 (1.211–1.930)

 < 0.001

1.109 (0.833–1.476)

0.478

SII

 < 577.7/ ≥ 577.7

1.466 (1.196–1.796)

 < 0.001

1.209 (0.886–1.649)

0.232

PNI

 < 41.5/ ≥ 41.5

0.554 (0.419–0.733)

 < 0.001

0.691 (0.505–0.944)

0.020

PAR

 < 5.7 × 109/ ≥ 5.7 × 109

1.470 (1.183–1.827)

 < 0.001

1.298 (1.014–1.661)

0.038

  1. HR hazard ratio, CI confidence interval.
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