Table 3 Univariable and multivariable Cox regression analysis for overall survival.

From: Prognostic significance of platelet-to-albumin ratio in patients with esophageal squamous cell carcinoma receiving definitive radiotherapy

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Gender

Male/Female

0.994 (0.790–1.250)

0.960

  

Age

 ≤ 70/ > 70

1.008 (0.812–1.251)

0.944

  

Location

Cervical + Upper/Middle + Lower

1.086 (0.870–1.356)

0.468

  

T stage

T2-3/T4

1.341 (1.091–1.648)

0.005

0.667 (0.421–1.057)

0.085

N stage

N0/N + 

1.223 (0.957–1.562)

0.107

  

cTNM stage

II + III/IV

1.461 (1.188–1.798)

 < 0.001

2.147 (1.350–3.414)

0.001

RT technique

2D-CRT/IMRT + 3D-CRT

0.769 (0.516–1.147)

0.199

  

Adjuvant chemotherapy

No/Yes

0.742 (0.597–0.923)

0.007

0.647 (0.515–0.813)

 < 0.001

Marrow depression

No/Yes

0.861 (0.701–1.057)

0.152

  

NLR

 < 2.62/ ≥ 2.62

1.333 (1.085–1.639)

0.006

1.108 (0.820–1.496)

0.505

PLR

 < 180/ ≥ 180

1.503 (1.187–1.902)

 < 0.001

1.095 (0.817–1.467)

0.545

SII

 < 577.7/ ≥ 577.7

1.440 (1.172–1.769)

 < 0.001

1.170 (0.852–1.606)

0.333

PNI

 < 41.5/ ≥ 41.5

0.581 (0.438–0.770)

 < 0.001

0.732 (0.532–1.007)

0.055

PAR

 < 5.7 × 109/ ≥ 5.7 × 109

1.480 (1.187–1.845)

 < 0.001

1.312 (1.021–1.685)

0.033

  1. HR hazard ratio, CI confidence interval.
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