Figure 3

Critical COVID-19 induces high titers of anti-SARS-CoV-2 IgG. (A) IgG titers specific to SARS-CoV-2 spike receptor-binding domain for COVID-19 and normal serum samples. (B) IgG titers of critically infected COVID-19 patients who either recovered from infection (living) or failed to recover (deceased), alongside 20 uninfected (normal) patients. Geometric mean and geometric SD are shown. Statistically significant differences as determined by Mann–Whitney test are indicated as p < 0.0001 (****), and p < 0.05 (*).