Table 1 Demographic and clinical characteristics of patients.
Variables | Training cohort | Validation cohort | ||
|---|---|---|---|---|
N = 1375 | N = 588 | |||
n | % | n | % | |
Age | ||||
< 55 | 162 | 11.7 | 89 | 15.1 |
55–66 | 480 | 35.0 | 200 | 34.0 |
> 66 | 733 | 53.3 | 299 | 50.9 |
> 66 | 733 | |||
Race | ||||
Black | 144 | 10.5 | 57 | 9.7 |
Other | 158 | 11.5 | 59 | 10.0 |
White | 1073 | 78.0 | 472 | 80.3 |
Sex | ||||
Male | 804 | 58.5 | 338 | 57.5 |
Female | 571 | 41.5 | 250 | 42.5 |
Primary site | ||||
Lower lobe | 413 | 30.1 | 192 | 32.7 |
Main bronchus | 63 | 4.6 | 26 | 4.4 |
Middle lobe | 68 | 4.9 | 31 | 5.3 |
Overlapping lesion of lung | 17 | 1.2 | 7 | 1.2 |
Upper lobe | 814 | 59.2 | 332 | 56.4 |
Laterality | ||||
Left | 613 | 44.6 | 213 | 36.2 |
Right | 762 | 55.4 | 375 | 63.8 |
Histological types | ||||
Adenocarcinoma | 752 | 54.7 | 322 | 54.8 |
Other | 245 | 17.8 | 109 | 18.5 |
Squamous cell carcinoma | 378 | 27.5 | 157 | 26.7 |
Grade | ||||
I | 65 | 4.7 | 26 | 4.4 |
II | 335 | 24.4 | 144 | 24.5 |
III | 941 | 68.4 | 401 | 68.2 |
IV | 34 | 2.5 | 17 | 2.9 |
T stage | ||||
T1 | 112 | 8.1 | 51 | 8.7 |
T2 | 388 | 28.2 | 156 | 26.5 |
T3 | 395 | 28.7 | 176 | 29.9 |
T4 | 480 | 35.0 | 205 | 34.9 |
N stage | ||||
No | 272 | 19.8 | 115 | 19.6 |
N1 | 122 | 8.9 | 42 | 7.1 |
N2 | 691 | 50.2 | 293 | 49.8 |
N3 | 290 | 21.1 | 138 | 23.5 |
Surgery | ||||
No | 41 | 3.0 | 568 | 96.6 |
Yes | 1334 | 97.0 | 20 | 3.4 |
Chemotherapy | ||||
No | 608 | 44.2 | 247 | 42.0 |
Yes | 767 | 55.8 | 341 | 58.0 |
Radiotherapy | ||||
No | 785 | 57.1 | 335 | 57.0 |
Yes | 590 | 42.9 | 253 | 43.0 |
Bone metastasis | ||||
No | 667 | 48.5 | 278 | 47.3 |
Yes | 708 | 51.5 | 310 | 52.7 |
Brain metastasis | ||||
No | 1004 | 73.0 | 442 | 75.2 |
Yes | 371 | 27.0 | 146 | 24.8 |
Lung metastasis | ||||
No | 881 | 64.1 | 384 | 65.3 |
Yes | 494 | 35.9 | 204 | 34.7 |
Tumor size | ||||
< 42 | 521 | 37.9 | 227 | 38.6 |
42–71 | 555 | 40.4 | 219 | 37.2 |
> 71 | 299 | 21.7 | 142 | 24.2 |
Insurance status | ||||
No | 45 | 3.3 | 12 | 2.0 |
Yes | 1330 | 96.7 | 576 | 98.0 |
Marital | ||||
No | 608 | 44.2 | 269 | 45.7 |
Yes | 767 | 55.8 | 319 | 54.3 |
