Figure 8 | Scientific Reports

Figure 8

From: Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug repurposing

Figure 8

Molecular docking results computed with autodock vina. Red colors indicated the strong binding affinities between target proteins and drug agents, and green colors indicated their weak bindings. (a) Image of binding affinities based on the top 50 ordered drug agents out of 90 in X-axis and ordered 15 target proteins (proposed) in Y-axis. (b) Image of binding affinities based on the proposed ordered 7 candidate drugs in X-axis and ordered 11 independent receptors (already published) in Y-axis. (c) Image of binding affinities based on the proposed ordered 7 candidate drugs in X-axis and original & protonated (at pH-7)* receptors in Y-axis, where * indicates the protonated receptors.

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