Figure 5
From: The effect of spermidine on autoimmunity and beta cell function in NOD mice
Daily oral spermidine treatment enhanced endogenous spermidine levels in male NOD mice. (a) Spermidine and (b) putrescine levels were analyzed in pancreas, pLN, spleen, thymus, heart, plasma and whole blood after 4 weeks of 10 mM spermidine treatment. Black triangles show ctrl mice (n = 8) and red circles show spd mice (n = 10). Data is shown as nmol/g and mean ± SD. Mann–Whitney U test or unpaired Student’s t-test was used as statistical analysis. p* < 0.05, p** < 0.01, p*** < 0.001, p**** < 0.0001.
