Figure 5

Evaluation of DFA and PL additivity with PAS using a colony-forming unit (CFU) assay. H37Rv wild-type bacteria were incubated with (a) DFA and (b) PL compounds at various concentrations, in presence or absence of PAS (100 nM). Aliquots were withdrawn at regular interval and plated on solid agar for CFU enumeration. Data shown here are for 7 days of incubation (see Fig. S18 for additional data at day 2) and represent average ± SD for plating made in duplicate. The horizontal dotted line indicates the CFU counts obtained at day 0 (7.06 ± 0.3).