Figure 3
(A) Decreased richness was observed in IBD marmosets (Observed OTUs and Chao1) compared to non-IBD marmosets similar to what is observed in humans. (B) Increases in PC1 relative to source-specific, non-IBD controls were observed in 3 of 4 sources. Red dot in violin plots represents the mean. (C) Bacteroides and Prevotella 9 levels are shown by source and IBD status. A lower overall and source-specific Bacteroides:Prevotella 9 ratio is observed in IBD cases regardless of source-specific differences in abundances of these two genera. (D) AUC of ROC for random forest models using serum chemistry and CBC show strong performance of models in classifying IBD progressors and non-progressors. Boxplots encompass the 25th and 75th percentiles of the distribution with the horizontal bar representing the median. *P < 0.05; **P < 0.01 and ***P < 0.001.
