Table 2 Top gene ontology sets in IBD.

(a) Biological processes upregulated in the Jejunum in IBD

GO:0002376

Immune system process

BP

1

7.30E−58

GO:0006955

Immune response

BP

1

7.75E−57

GO:0045321

Leukocyte activation

BP

1

7.62E−47

GO:0046649

Lymphocyte activation

BP

0.9999998

4.13E−46

GO:0042110

T cell activation

BP

0.9999956

1.32E−43

GO:0002682

Regulation of immune system process

BP

0.9999999

1.42E−42

GO:0001775

Cell activation

BP

0.9999997

3.75E−42

GO:0002250

Adaptive immune response

BP

0.9999995

9.97E−39

GO:0002684

Positive regulation of immune system process

BP

1

5.02E−36

GO:0050776

Regulation of immune response

BP

1

1.07E−35

GO:0006952

Defense response

BP

0.9999512

6.45E−34

GO:0002252

Immune effector process

BP

1

2.64E−31

GO:0050778

Positive regulation of immune response

BP

1

1.02E−28

GO:0002521

Leukocyte differentiation

BP

0.9999927

2.24E−28

GO:0007159

Leukocyte cell–cell adhesion

BP

0.9996237

4.13E−27

(b) Biological processes upregulated in the Jejunum in non-IBD

GO:0003008

System process

BP

3.89E−36

5.12E−01

GO:0099537

Trans-synaptic signaling

BP

8.64E−24

9.59E−01

GO:0032501

Multicellular organismal process

BP

1.40E−23

7.31E−07

GO:0099536

Synaptic signaling

BP

1.85E−23

9.63E−01

GO:0048731

System development

BP

4.31E−23

7.45E−05

GO:0044057

Regulation of system process

BP

8.25E−23

9.29E−01

GO:0098916

Anterograde trans-synaptic signaling

BP

1.23E−22

9.51E−01

GO:0007268

Chemical synaptic transmission

BP

1.23E−22

9.51E−01

GO:0006936

Muscle contraction

BP

7.02E−21

8.93E−01

GO:0032502

Developmental process

BP

1.20E−20

4.77E−04

GO:0007399

Nervous system development

BP

1.33E−20

5.61E−01

GO:0048468

Cell development

BP

2.52E−20

1.09E−01

GO:0048856

Anatomical structure development

BP

1.43E−19

7.56E−04

GO:0003012

Muscle system process

BP

3.50E−19

9.69E−01

GO:0007275

Multicellular organism development

BP

4.19E−19

4.20E−04