Table 4 Regressions between regional basal ganglia gray matter volume, motor learning, pattern of substance use, and risky behavior.
From: Characterization of basal ganglia volume changes in the context of HIV and polysubstance use
Group | t-value | Cluster size (voxels) | MNI peak coordinates (x, y, z) | ROI mask location | |
|---|---|---|---|---|---|
Motor learning | |||||
Loop drawing (Δ trials 1 -8) | HIV + /POLY + | 7.15 | 15 | − 12, 22, 6 | Caudate (L) |
9.98 | 43 | 14, 21, 10 | Caudate (R) | ||
6.19 | 23 | 30, 8, 2 | Putamen (R) | ||
Substance use duration | |||||
Opioids (years) | HIV-/POLY + | − 4.52 | 119 | 22, − 2, − 2 | GPe (R) |
− 4.40 | 80 | 2, − 16, − 4 | SNc (R) | ||
− 4.78 | 68 | 15, − 2, 3 | GPi (R) | ||
− 3.86 | 67 | 15, 6, − 15 | NAc (R) | ||
− 3.89 | 59 | − 15, 2, − 10 | GPe (L) | ||
− 4.60 | 59 | − 6, 6, − 12 | NAc (L) | ||
− 4.43 | 17 | − 12, 4, 6 | Caudate (L) | ||
− 4.06 | 14 | 21, 2, − 6 | Putamen (R) | ||
− 3.53 | 11 | − 21, − 3, − 2 | GPi (L) | ||
− 3.72 | 10 | 2, − 15, − 15 | VTA (R) | ||
Stimulants (years) | HIV + /POLY + | 6.34 | 17 | − 27, − 4, 6 | GPe (L) |
7.12 | 5 | − 28, − 3, 8 | Putamen (L) | ||
Substance use frequency | |||||
Opioid weighted frequency (scaled frequency) | HIV-/POLY + | − 4.15 | 89 | − 24, − 4, 0 | GPe (L) |
− 3.98 | 41 | − 21, − 6, 2 | GPi (L) | ||
− 4.96 | 40 | − 3, 6, − 8 | NAc (L) | ||
− 2.99 | 17 | 15, 10, − 15 | NAc (R) | ||
Risky behavior | |||||
RAB* (total score) | HIV-/POLY + | 7.18 | 6 | − 18, 10, − 3 | Putamen (L) |
HIV + /POLY- | − 5.64 | 53 | − 3, − 20, − 9 | SNc (L) | |
− 3.30 | 8 | 2, − 18, − 16 | VTA (L) | ||
