Table 5 Gray matter ROI volume differences between controls versus clinical groups within the basal ganglia.

From: Characterization of basal ganglia volume changes in the context of HIV and polysubstance use

Controls (HIV-/POLY−) vs. clinical groups

t-value

Cluster size (voxels)

MNI peak coordinates (x, y, z)

Location

HIV-/POLY + 

 

− 3.69

96

− 18, 2, 2

GPe (L)

 

− 3.87

92

− 18, − 2, 3

GPi (L)

 

− 3.52

10

− 6, 8, 4

Caudate (L)

HIV + /POLY + 

 

− 3.34

13

− 21, 4, 4

GPe (L)

HIV + /POLY−

 

− 3.28

10

− 20, 3, 3

GPe (L)

  1. Data represent clusters with significant GM reduction in the basal ganglia in each clinical group relative to that of controls (p < 0.05 FWE with a cut-off threshold of ≥ 5 voxels) in each ROI within the basal ganglia. L = left; R = right.