Table 6 Top-10 most similar drug-term nodes.
From: A knowledge graph of clinical trials (\(\mathop {\mathtt {CTKG}}\limits\))
Similarity | Similar nodes | Possible evidence |
|---|---|---|
0.997 | ABT-267 | Both ABT-267 and Macrocyclic Compounds could be used to treat Hepatitis C Virus (HCV) infection21,22 |
Macrocyclic Compounds | ||
0.996 | Pulmonary Surfactants | Pulmonary Surfactants is a type of Surface-Active Agents41 |
Surface-Active Agents | ||
0.995 | Phenylethyl Alcohol | Phenylethyl Alcohol and LY2216684 are studied together in study NCT00922636, NCT01243957 and NCT01380691 |
LY2216684 | ||
0.994 | Thioguanine | Thioguanine is a substitute of Mercaptopurine in treating childhood lymphoblastic leukaemia42 |
Mercaptopurine | ||
0.993 | Cilastatin | Cilastatin and Imipenem are commonly used together as a treatment for serious infections43 |
Imipenem | ||
0.985 | Metylperon | Metylperon is an atypical antipsychotic of the Butyrophenone chemical class44 |
Butyrophenones | ||
0.983 | Ubiquinone | Ubiquinone is a form of Coenzyme Q1045 |
Coenzyme Q10 | ||
0.982 | PHiD-CV Vaccine | |
VAXELIS | ||
0.982 | Propafenone | Both Propafenone and Sotalol could maintain sinus rhythm for patients with recurrent symptomatic atrial fibrillation48 |
Sotalol | ||
0.980 | SNAP25 Protein | SNAP25 Protein could block Acetylcholine from releasing at the neuromuscular junction49 |
Acetylcholine |
