Figure 4 | Scientific Reports

Figure 4

From: Natural antibody IgG levels are associated with HBeAg-positivity and seroconversion in chronic hepatitis B patients treated with entecavir

Figure 4

Levels of IgG subtypes and complement in serum of CHB patients with loss of HBeAg and detection of anti-HBe antibody, seroconversion (SC) and non-SC. Serum levels of IgG1–4, complement C3, and C1q were measured in SC patients (n = 31, orange dots) and non-SC patients (n = 45, green dots). Shaded areas indicate 95% confidence intervals around the regression lines. Bar graphs represent concentration of IgG1–4, complement C3 and C1q in pre-treatment (dark orange), post-treatment (light orange) of SC and pre-treatment (dark green), post-treatment (light green) of non-SC patients. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001.

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