Figure 3
From: The possible role of hypoxia in the affected tissue of relapsed clubfoot
The fold change in the relative mRNA expression of selected genes (ACTA2, TGFB1, HIF1A, MMP2, FN1) in the M-side versus the L-side of the relapsed clubfoot tissue. A significant increase in expression was detected in the contracted medial side, in comparison with the non-contracted lateral side. The gene expression is normalized to the reference gene B2M and the mean expression value of the particular gene in the corresponding L-side tissue sample. Data are presented on a log scale as mean ± SD. The significance level is indicated as follows: *p < 0.05, **p < 0.01, ***p < 0.005.
