Figure 7
From: Effects of cadmium on oxidative stress and cell apoptosis in Drosophila melanogaster larvae
Effects of Cd on the gene expression of pro-apoptotic and anti-apoptotic genes in Drosophila third instar larvae. Real time PCR results showing the expression of pro-apoptotic genes, (A): Debcl; (B): hid; (C): rpr; (D): p53; (E): Sce; (F): Diap1; (Mean ± SD, n = 3, 6 larvae per sample, **P < 0.01, ns = not significant). Compared with the control the mRNA expression of Debcl, hid, rpr, and p53 increased at higher Cd concentrations (4.5 mg/kg and 9 mg/kg) (P < 0.01) (A–D). The expression of the anti-apoptotic gene Sce was significantly reduced at higher Cd concentrations (4.5 mg/kg and 9 mg/kg) (P < 0.01) (E) . The expression of anti-apoptotic gene Diap1 showed a downward trend and decreased significantly in 2.25 mg/kg, 4.5 mg/kg and 9 mg/kg treatment groups compared with the control group (P < 0.01) (F).
