Figure 5

Representative flow chart of the optical coherence tomography angiography image processing of the superficial capillary plexus (SCP), deep capillary plexus (DCP), and choriocapillaris (CC) using FIJI software (an expanded version of ImageJ), version 1.52u (National Institutes of Health, Bethesda, MD, USA). The SCP and DCP images were duplicated, and one image was binarized with two different threshold values (“hessian” and “Huang’s fuzzy”, respectively). The other image was binarized using median local thresholding. The resultant binarized image was then generated, and only pixels that existed on two binarized images were included. The MaxEntropy threshold was applied to binarized SCP images. The obtained thresholded images were then merged with binarized DCP and CC images for identification and removal of the superficial retinal large vessels.