Figure 2 | Scientific Reports

Figure 2

From: Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways

Figure 2

The expression of TXNIP is upregulated during fasting. The expression of TXNIP mRNA and protein in fed or fasted states was evaluated by RT-qPCR or western blotting. TXNIP mRNA (a) and protein (b) expression increased significantly in the fasted state in WT mice. TXNIP mRNA and protein expression was completely suppressed in TXNIP-KO mice in both states. *p < 0.05, **p < 0.01 (in each group, six mice were used for RT-qPCR, and ten were used for western blot analysis). TXNIP thioredoxin-interacting protein, WT wild-type, KO knockout mice.

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