Figure 1
From: Upregulation of Cytotoxic T-cells in pediatric patients with Gaucher disease
Flow cytometric detection of NK, NKT cells, and subtypes of T cytotoxic cells. (A) Scatter histogram was used to define the lymphocytes population (R1). (B) The expression of CD3 and CD16/CD56 on lymphocytes was assessed to detect NK and NKT cells. (C) The expression of CD8 was assessed on lymphocytes and then gated for further assessment of intracellular cytokines. (D) The expression of IL-4 and IFNγ on CD8 T cells. Tc1 cells (IFN-γ (+) IL-4(−) CD8 T cells), and Tc2 cells (IFN-γ (−) IL-4(+) CD8 T cells).
