Table 1 Descriptive clinical and laboratory data of GD patients.
From: Upregulation of Cytotoxic T-cells in pediatric patients with Gaucher disease
Item | Patients n = 20 | Control n = 20 | p-value |
|---|---|---|---|
Weight (Kg) | 32.25 ± 12.6 | 42.1 ± 17.3 | 0.046* |
Age (years) | 10.8 ± 3.81 | 11.02 ± 3.87 | 0.086 |
Male/ Female | 9/11 | 11/9 | 0.56 |
Family history (yes/no) | 14/6 | – | – |
Liver span (cm) | 11.47 ± 2.91 | 9.5 ± 1.68 | 0.02* |
Spleen span (cm) | 13.3 ± 5.04 | 7.5 ± 2.33 | < 0.01* |
Skeletal involvement | |||
Osteopenia | 18/20 | ||
Erlenmeyer flask deformity | 3/20 | ||
Fracture | 1/20 | – | – |
Kyphoscoliosis | 1/20 | ||
Pigeon chest | 1/20 | ||
Recurrent chest infection | 5/20 | – | – |
Interstitial pulmonary diseases | 3/20 | – | – |
Neurological manifestations | 14/20 | ||
Squint | 3/20 | – | – |
EEG changes | 8/20 | ||
Convulsion | 6/20 | ||
ß-Glucocerebrosidase (Mmol/gm/h) (before ERT) | 0.32 ± 0.172 | – | – |
Chitotriosidase (Mmol/l/h) (before ERT) | 3978.34 ± 4051.4 | – | – |
