Figure 3

Tumor growth is correlated with systemic regulation of glucose, leptin and ghrelin. From mice in study design 1, serum concentrations and association to tumor volume of (A) insulin, (B) glucose, (C) leptin and (D) ghrelin were determined. Statistical significance was determined by 2-way ANOVA with Tukey’s post hoc test and linear regression analyses. P values for diet and EX describe the results of the 2-way ANOVA, while individual stars indicate difference from control (CON) group within each diet group. **p < 0.01, ***p < 0.001.