Table 1 Characteristics of patients according to the primary outcome (mortality at 30 days).
Variable | Alive (N = 2835) | Dead (N = 381) | P value |
|---|---|---|---|
Demographics and co-morbidity (%) | |||
Age > 66 years | 1236 (43.8) | 331 (86.9) | < 0.001 |
Male sex | 1642 (58.2) | 242 (63.5) | 0.049 |
Chronic heart disease | 638 (22.5) | 210 (55.1) | < 0.001 |
Diabetes mellitus | 529 (18.7) | 117 (30.7) | < 0.001 |
Haematological disease | 165 (5.8) | 41 (10.8) | < 0.001 |
Chronic kidney disease | 266 (9.4) | 130 (34.1) | < 0.001 |
Chronic liver disease | 203 (7.2) | 32 (8.4) | 0.383 |
Hypertension | 1228 (43.3) | 262 (68.8) | < 0.001 |
Solid tumour | 395 (13.9) | 108 (28.3) | < 0.001 |
Solid organ transplantation | 62 (2.2) | 13 (3.4) | 0.137 |
HIV infection | 35 (1.2) | 6 (1.6) | 0.623 |
Chronic lung disease | 651 (23) | 130 (34.1) | < 0.001 |
Clinical characteristics and biomarkers at admission (%) | |||
Temperature > 37ºC | 1356 (48.6) | 130 (28.2) | < 0.001 |
Oxygen saturation > 94% | 1346 (48.4) | 98 (28.7) | < 0.001 |
LDH > 305 U/mL | 1283 (48) | 210 (62.7) | < 0.001 |
Creatinine > 0.92 mg/dL | 1280 (45.5) | 284 (76.5) | < 0.001 |
Lymphocyte count > 800 cells/mm3 | 1444 (51.3) | 134 (36.1) | < 0.001 |
C-reactive protein > 7.52 mg/dL | 1323 (47.5) | 248 (68.3) | < 0.001 |
Critical support and treatment (%) | |||
Intensive Care Unit admission | 661 (23.3) | 123 (32.3) | < 0.001 |
Invasive mechanical ventilation | 267 (9.4) | 63 (16.5) | < 0.001 |
Remdesivir | 519 (18.3) | 30 (7.9) | < 0.001 |
Dexamethasone the first 5 days | 882 (31.1) | 136 (35.7) | 0.071 |
Tocilizumab the first 5 days | 495 (17.5) | 54 (14.2) | 0.109 |
