Figure 4
From: Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment
(a) Biofilm disruption assay in Transwell plates showing LIVE/DEAD (green/red, respectively) stained confocal laser scanning microscopy (CLSM) images (aerial and cross sectional views, scale bar, 30 μm) of 24 h P. aeruginosa NH57388A biofilms, following 24 h treatment with colistin ± 1% OligoG added onto the artificial sputum medium surface. (b) COMSTAT image analysis of the CLSM images (± SEM; n = 15). Significant difference is indicated by *, where *p < 0.05 compared to untreated control.
