Figure 2 | Scientific Reports

Figure 2

From: In vivo imaging with two-photon microscopy to assess the tumor-selective binding of an anti-CD137 switch antibody

Figure 2

Human CD137 expression in LLC1/OVA/hGPC3-bearing hCD137-KI mice. Tumors and spleens were sampled at 24 h after administration of PBS (closed symbols) or an isotype control antibody (open symbols). (A) Human CD137 expression on CD45+ cells in tumor and spleen tissues. The individual values and mean for each tissue are shown. **P < 0.01 by t test. (B) Human CD137 expression on each type of cell. The percentage of human CD137-positive cells for each cell type was calculated by flow cytometry. The individual values and mean for each cell type are shown.

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