Figure 1 | Scientific Reports

Figure 1

From: Disrupted structural network of inferomedial temporal regions in relapsing–remitting multiple sclerosis compared with neuromyelitis optica spectrum disorder

Figure 1

The two disrupted subnetworks in the multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) groups as identified through network-based statistics. Significantly different connections between (A) three groups (MS, NMOSD, healthy controls [HC]), (B) MS and HC, (C) NMOSD and HC, and (D) MS and NMOSD were displayed; each edge was disrupted in MS or NMOSD compared with HC and there were no edges with increased edge weights in NMOSD compared with MS. The left column displays the lateral view of the left hemisphere, the middle column displays the transverse views of both hemispheres, and the right column displays the lateral view of the right hemisphere. The blue and red circles are the brain regions of subnetworks 1 and 2, respectively. The orange lines are the edges that connect each region. HIP hippocampus, PHG parahippocampal gyrus, AMYG amygdala, CAL calcarine fissure, CUN cuneus, LING lingual gyrus, SOG superior occipital gyrus, MOG middle occipital gyrus, FFG fusiform gyrus, SPG superior parietal gyrus, ANG angular gyrus, PCUN precuneus, PCL paracentral lobule, THA thalamus, STG superior temporal gyrus, TPOsup temporal pole: superior temporal gyrus, MTG middle temporal gyrus, TPOmid temporal pole: middle temporal gyrus, ITG inferior temporal gyrus.

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