Table 3 Biochemical parameters and arterial pressure of Prader–Willi syndrome (PWS) patients at baseline, after 3 and 6 years follow-up.
T0 (no. 60) | T3 (no. 60) | T6 (no. 60) | ΔT0-T3 | ΔT0-T6 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | (SD) | Mean | (SD) | Mean | (SD) | diff | (95%CI) | diff | (95%CI) | ||
Glycemia (mg/dl) | R | 86 | (16) | 84 | (13) | 85 | (11) | − 2 | (3 to − 7) | − 1 | (3 to − 6) |
S | 94 | (19) | 103 | (30) | 121* | (52) | 9 | (25 − 7) | 27 | (56 − 3) | |
N | 93 | (26) | 97 | (34) | 94 | (20) | 3 | (10 to − 4) | 1 | (15 to − 14) | |
Cholesterol (g/l) | R | 181 | (29) | 186 | (36) | 181 | (34) | 5 | (19 to − 9) | − 1 | (10 to − 11) |
S | 178 | (40) | 195 | (45) | 180 | (28) | 17 | (58 to − 24) | 1 | (27 to − 23) | |
N | 189 | (33) | 183 | (30) | 184 | (32) | − 6 | (9 to − 21) | − 5 | (13 to − 23) | |
HDL (mg/dl) | R | 51 | (12) | 52 | (12) | 52 | (14) | 1 | (6 to − 5) | 1 | (6 to − 4) |
S | 52 | (15) | 50 | (13) | 55 | (14) | − 2 | (5 to − 9) | 2 | (9 to − 4) | |
N | 51 | (14) | 48 | (15) | 48 | (11) | − 3 | (3 to − 8) | − 3 | (3 to − 9) | |
Triglycerides (mg/dl) | R | 95 | (32) | 93 | (35) | 101 | (42) | − 2 | (11 to − 14) | 6 | (21 to − 10) |
S | 97 | (45) | 107 | (67) | 110 | (55) | 10 | (33 to − 14) | 13 | (42 to − 17) | |
N | 105 | (41) | 96 | (41) | 101 | (35) | − 9 | (10 to − 28) | − 4 | (17 to − 26) | |
LDL (mg/dl) | R | 119 | (25) | 120 | (31) | 115 | (31) | 1 | (13 to − 12) | − 4 | (8 to − 16) |
S | 111 | (32) | 117 | (36) | 113 | (24) | 6 | (22 to − 10) | 2 | (24 to − 20) | |
N | 121 | (36) | 122 | (26) | 125 | (32) | 1 | (19 to − 17) | 4 | (22 to − 14) | |
HbA1c (%) | R | 5.6 | (0.4) | 5.5 | (0.5) | 5.5 | (0.6) | − 0.1 | (0.1 to − 0.3) | − 0.2 | (0.1 to − 0.5) |
S | 6.0 | (0.7) | 6.1 | (1.2) | 6.4 | (1.9) | 0.2 | (0.8 to − 0.5) | 0.4 | (1.6 to − 0.8) | |
N | 5.9 | (1) | 5.8 | (1.1) | 5.7 | (0.7) | − 0.1 | (0.4 to − 0.5) | − 0.2 | (0.3 to − 0.6) | |
SAP (mmHg) | R | 129 | (19) | 121 | (12) | 122 | (10) | − 8 | (4 to − 19) | − 7 | (4 to − 19) |
S | 121 | (14) | 122 | (12) | 122 | (6) | 1 | (12 to − 11) | 1 | (10 to − 8) | |
N | 123 | (8) | 126 | (9) | 130 | (1) | 3 | (10 to − 4) | 7 | (15 to − 1) | |
DAP (mmHg) | R | 81 | (9) | 78 | (10) | 78 | (8) | − 3 | (3 to − 9) | − 3 | (2 to − 8) |
S | 78 | (7) | 82 | (10) | 78 | (5) | 4 | (12 to − 4) | 0 | (6 to − 6) | |
N | 80 | (8) | 79 | (7) | 78 | (6) | − 1 | (4 to − 6) | − 2 | (3 to − 8) | |