Table 3 Biochemical parameters and arterial pressure of Prader–Willi syndrome (PWS) patients at baseline, after 3 and 6 years follow-up.

From: Predictive factors of responsiveness to a body weight reduction program in Prader–Willi patients at 6 years of follow-up

  

T0 (no. 60)

T3 (no. 60)

T6 (no. 60)

ΔT0-T3

ΔT0-T6

Mean

(SD)

Mean

(SD)

Mean

(SD)

diff

(95%CI)

diff

(95%CI)

Glycemia (mg/dl)

R

86

(16)

84

(13)

85

(11)

− 2

(3 to − 7)

− 1

(3 to − 6)

S

94

(19)

103

(30)

121*

(52)

9

(25 − 7)

27

(56 − 3)

N

93

(26)

97

(34)

94

(20)

3

(10 to − 4)

1

(15 to − 14)

Cholesterol (g/l)

R

181

(29)

186

(36)

181

(34)

5

(19 to − 9)

− 1

(10 to − 11)

S

178

(40)

195

(45)

180

(28)

17

(58 to − 24)

1

(27 to − 23)

N

189

(33)

183

(30)

184

(32)

− 6

(9 to − 21)

− 5

(13 to − 23)

HDL (mg/dl)

R

51

(12)

52

(12)

52

(14)

1

(6 to − 5)

1

(6 to − 4)

S

52

(15)

50

(13)

55

(14)

− 2

(5 to − 9)

2

(9 to − 4)

N

51

(14)

48

(15)

48

(11)

− 3

(3 to − 8)

− 3

(3 to − 9)

Triglycerides (mg/dl)

R

95

(32)

93

(35)

101

(42)

− 2

(11 to − 14)

6

(21 to − 10)

S

97

(45)

107

(67)

110

(55)

10

(33 to − 14)

13

(42 to − 17)

N

105

(41)

96

(41)

101

(35)

− 9

(10 to − 28)

− 4

(17 to − 26)

LDL (mg/dl)

R

119

(25)

120

(31)

115

(31)

1

(13 to − 12)

− 4

(8 to − 16)

S

111

(32)

117

(36)

113

(24)

6

(22 to − 10)

2

(24 to − 20)

N

121

(36)

122

(26)

125

(32)

1

(19 to − 17)

4

(22 to − 14)

HbA1c (%)

R

5.6

(0.4)

5.5

(0.5)

5.5

(0.6)

− 0.1

(0.1 to − 0.3)

− 0.2

(0.1 to − 0.5)

S

6.0

(0.7)

6.1

(1.2)

6.4

(1.9)

0.2

(0.8 to − 0.5)

0.4

(1.6 to − 0.8)

N

5.9

(1)

5.8

(1.1)

5.7

(0.7)

− 0.1

(0.4 to − 0.5)

− 0.2

(0.3 to − 0.6)

SAP (mmHg)

R

129

(19)

121

(12)

122

(10)

− 8

(4 to − 19)

− 7

(4 to − 19)

S

121

(14)

122

(12)

122

(6)

1

(12 to − 11)

1

(10 to − 8)

N

123

(8)

126

(9)

130

(1)

3

(10 to − 4)

7

(15 to − 1)

DAP (mmHg)

R

81

(9)

78

(10)

78

(8)

− 3

(3 to − 9)

− 3

(2 to − 8)

S

78

(7)

82

(10)

78

(5)

4

(12 to − 4)

0

(6 to − 6)

N

80

(8)

79

(7)

78

(6)

− 1

(4 to − 6)

− 2

(3 to − 8)

  1. Measurements are reported as mean and standard deviation (SD), while changes are reported as mean difference and 95% confidence interval (CI). *: significantly different from the responsive subgroup (p < 0.05); N: non-responsive patients; HDL: high density lipoprotein; LDL: low density lipoprotein; HbA1c: glycated haemoglobin; SAP: systolic arterial pressure; DAP: diastolic arterial pressure.