Table 4 Multi-variate analysis for late GU and GI toxicity grade 2 ≤ using Cox proportional hazards model.
Variable | Strata | GI | GU | ||||
|---|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | ||
Age, years | ≤ 70 | 1 | (Referent) | – | 1 | (Referent) | – |
71 ≤ | 1.31 | 0.74–2.33 | 0.35 | 1.14 | 0.74–1.75 | 0.56 | |
T classification | ≤ 2 | 1 | (Referent) | – | 1 | (Referent) | – |
3 ≤ | 0.82 | 0.38–1.78 | 0.62 | 0.8 | 0.59–1.08 | 0.15 | |
Gleason score | ≤ 7 | 1 | (Referent) | – | 1 | (Referent) | – |
8 ≤ | 0.7 | 0.33–1.47 | 0.34 | 1.12 | 0.85–1.48 | 0.43 | |
Pretreatment PSA (ng/mL) | ≤ 10 | 1 | (Referent) | – | 1 | (Referent) | – |
10 < | 1.23 | 0.67–2.24 | 0.51 | 1.18 | 0.91–1.52 | 0.2 | |
Hormonal therapy | No | 1 | (Referent) | – | 1 | (Referent) | – |
Yes | 0.64 | 0.29–1.42 | 0.27 | 1.14 | 0.74–1.75 | 0.56 | |
Acute toxicty grade 2 ≤ | No | 1 | (Referent) | – | 1 | (Referent) | – |
Yes | 6.76 | 1.94–23.59 | 0.0027 | 2.19 | 1.69–2.84 | < 0.0001 | |
Treatment modalities | BT ± EBRT | 1 | (Referent) | – | 1 | (Referent) | – |
UHF | 2.37 | 1.04–5.39 | 0.04 | 0.76 | 0.43–1.35 | 0.35 | |
