Figure 2

The association between body weight cycling and the risk of type 2 diabetes and hypertension according to sex, smoking status, baseline age, and obesity. Incident diabetes was defined as the prescription of antidiabetic medication or fasting blood sugar ≥ 126 mg/dL. Hypertension was defined as the prescription of hypertensive medication or systolic or diastolic blood pressure ≥ 140/90 mmHg. The hazard ratio was calculated with a Cox proportional hazards regression for different subgroups including sex (top left, a), smoking status (top right, b), age group (bottom left, c), and body mass index (bottom right, d) after adjusting for systolic blood pressure, fasting blood sugar, total cholesterol, smoking status, alcohol consumption, physical activity, past medical history, and family history. Dots and error bars indicate the hazard ratio and 95% confidence interval, respectively.