Table 3 Results for the multivariate regression models for the weighted and Box–Cox-transformed values of transaminases.
Outcome | Variables | Estimate (β) | SE | edf | P |
|---|---|---|---|---|---|
AST (UI/L) | Intercept | − 2.697 | 1.090 | 1.000 | 0.014 |
Exitus (Ref: Alive) | 0.060 | 0.108 | 1.000 | 0.579 | |
D-dimer | 0.952 | 0.452 | 1.000 | 0.036 | |
IL-6 | 0.102 | 0.029 | 1.000 | < 0.001 | |
s(Age) | See Fig. 2 | 1.000 | 0.715 | ||
s(Time) (Alive) | See Fig. 2 | 4.892 | < 0.001 | ||
s(Time) (Deceased) | See Fig. 2 | 1.001 | 0.270 | ||
ALT (UI/L) | Intercept | − 1.657 | 0.713 | 1.000 | 0.020 |
Exitus (Ref: Alive) | − 0.251 | 0.126 | 1.000 | 0.046 | |
CRP | − 0.008 | 0.001 | 1.000 | < 0.001 | |
D-dimer | 0.579 | 0.265 | 1.000 | 0.029 | |
s(Age) | See Fig. 2 | 2.988 | 0.003 | ||
s(Time) (Alive) | See Fig. 2 | 4.689 | < 0.001 | ||
s(Time) (Deceased) | See Fig. 2 | 3.965 | < 0.001 | ||
GGT (UI/L) | Intercept | − 4.028 | 1.135 | 1.000 | < 0.001 |
Sex (Ref: Male) | 0.339 | 0.126 | 1.000 | 0.008 | |
Exitus(Ref: Alive) | − 0.131 | 0.190 | 1.000 | 0.490 | |
CRP | − 0.002 | 0.002 | 1.000 | 0.373 | |
D-dimer | 1.549 | 0.465 | 1.000 | < 0.001 | |
IL-6 | − 0.017 | 0.030 | 1.000 | 0.566 | |
Lymphocytes | − 0.007 | 0.003 | 1.000 | 0.021 | |
s(Age) | See Fig. 2 | 2.777 | 0.085 | ||
s(Time) (Alive) | See Fig. 2 | 5.103 | < 0.001 | ||
s(Time) (Deceased) | See Fig. 2 | 4.194 | < 0.001 | ||
ALP (UI/L) | Intercept | − 0.584 | 0.055 | 1.000 | < 0.001 |
Exitus (Ref: Alive) | 0.242 | 0.131 | 1.000 | 0.065 | |
s(Age) | See Fig. 2 | 2.054 | 0.569 | ||
s(Time) (Alive) | See Fig. 2 | 4.397 | 0.004 | ||
s(Time) (Deceased) | See Fig. 2 | 3.871 | < 0.001 | ||
