Figure 7 | Scientific Reports

Figure 7

From: Protective effect of ethanolic extract of Echinacea purpurea contained nanoparticles on meniscal/ligamentous injury induced osteoarthritis in obese male rats

Figure 7

(a) Incapacitance test in osteoarthritis rats fed different doses of Nano-EE and EE after 6 weeks. Data are shown as the mean (n = 6 rats/group). p < 0.05 (*), p < 0.01 (**) vs. OBOA. p < 0.05 (#), p < 0.01 (##) represent significantly different between EE5X and Nano-EE5X. (b) Histology staining (Safranin O) of OA rats after different doses of Nano-EE and EE after 6 weeks. The scale bar length is 500 µm. The knee joints of rats with OA were stained with Fast Green/Safranin-O. (c) OARSI score of cartilage tissues. Grade 0: surface intact, cartilage morphology intact, grade 1: surface intact, grade 2: surface discontinuity, grade 3: vertical fissures (clefts), grade 4: erosion, grade 5: denudation, grade 6: deformation.

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