Table 3 Top 25 over-represented functional classes for miRNA targets.

From: Influence of air pollutants on circulating inflammatory cells and microRNA expression in acute myocardial infarction

Gene ontology biological process

p value *

Neg regulation of cardiac muscle cell differentiation

3.51E−04

Neg regulation of cardiocyte differentiation

1.04E−04

Pos regulation of cardiac epithelial to mesenchymal transition

1.53E−02

Coronary artery morphogenesis

1.53E−02

Foregut morphogenesis

2.35E−02

Regulation of cardiac epithelial to mesenchymal transition

2.35E−02

Regulation of Wnt signaling pathway involved in heart development

2.35E−02

Negative regulation of cell size

3.47E−02

Positive regulation of fibroblast migration

3.63E−04

Notch signaling involved in heart development

4.98E−02

Regulation of cardiac muscle cell differentiation

7.42E−04

Positive regulation of macrophage differentiation

7.16E−03

Positive regulation of ER unfolded protein response

7.16E−03

Regulation of cardiocyte differentiation

2.44E−07

Pericardium development

1.49E−04

Negative regulation of DNA damage response

9.88E−03

Pos regulation of leukocyte adhesion to vascular endothelial cell

1.49E−04

Regulation of cell communication by electrical coupling

9.88E−03

Positive regulation of nitric-oxide synthase biosynthetic process

1.34E−02

Cell surface receptor sig pathway involved in heart development

2.73E−04

Aortic valve morphogenesis

8.17E−07

Regulation of nitric-oxide synthase biosynthetic process

2.53E−03

Positive regulation in cellular response to chemical stimulus

3.62E−04

Regulation of leukocyte adhesion to vascular endothelial cell

6.83E−05

Interleukin-6-mediated signaling pathway

2,35E−02

  1. *Bonferroni adjusted p value.