Table 2 Comparison of retinal layer thicknesses in healthy controls and patients with pediatric and juvenile craniopharyngioma.

From: Parafoveal and peripapillary vessel density in pediatric and juvenile craniopharyngioma patients

Variables

Patients (n = 15)

Healthy controls (n = 18)

Estimate (SE)

95% CI

Adjusted p-value*

pRNFL thickness (μm)

Average

70.75 ± 16.55

101.33 ± 6.90

− 33.26 (4.53)

− 42.52, − 24.00

< 0.0001

Superior

91.93 ± 26.47

130.44 ± 17.46

− 41.59 (7.69)

− 57.33, − 25.85

< 0.0001

Inferior

89.47 ± 27.00

123.72 ± 14.35

− 40.00 (7.42)

− 55.18, − 24.83

< 0.0001

Nasal

51.53 ± 12.92

66.56 ± 8.23

− 16.03 (4.15)

− 24.52, − 7.54

0.0060

Temporal

50.07 ± 11.51

84.61 ± 22.74

− 35.43 (7.02)

− 49.78, − 21.07

< 0.0001

GCIPL thickness (μm)

Average

64.54 ± 12.10

83.56 ± 3.87

− 21.46 (2.89)

− 27.38, − 15.53

< 0.0001

Superior

61.77 ± 11.99

83.17 ± 4.90

− 24.47 (3.00)

− 30.63, − 18.31

< 0.0001

Inferior

63.46 ± 12.98

82.17 ± 4.83

− 20.39 (3.21)

− 26.97, − 13.80

< 0.0001

Nasal

59.73 ± 13.46

85.17 ± 5.12

− 28.08(3.56)

− 35.38, − 20.78

< 0.0001

Temporal

70.96 ± 13.41

82.61 ± 4.02

− 14.23 (3.22)

− 20.83, − 7.62

0.0010

  1. pRNFL peripapillary retinal nerve fiber layer, GCIPL ganglion cell-inner plexiform layer, SE standard error, CI confidence interval.
  2. Values are shown as mean ± standard deviation.
  3. *P-value was estimated by linear regression analysis with adjustments for age and spherical equivalent refractive errors and Bonferroni correction magnified by 10.
  4. Boldface indicates statistical significance.