Table 3 Comparison of superficial, deep retinal capillary plexus and radial peripapillary capillary segment vessel densities between patients with pediatric and juvenile CP and healthy controls.

From: Parafoveal and peripapillary vessel density in pediatric and juvenile craniopharyngioma patients

 

Patients (n = 15)

Healthy controls (n = 18)

Estimate (SE)

95% CI

Adjusted p-value*

SRCP, % area

Average

46.61 ± 2.65

49.76 ± 1.32

− 3.61 (0.76)

− 5.16, − 2.06

< 0.0001

Superior

47.31 ± 4.27

50.15 ± 3.20

− 3.95 (1.37)

− 6.74, − 1.15

0.1080

Inferior

46.87 ± 5.16

50.37 ± 3.01

− 3.76 (1.57)

− 6.99, − 0.54

0.3525

Nasal

45.05 ± 3.43

49.30 ± 1.84

− 4.86 (1.00)

− 6.90, − 2.81

 < 0.0001

Temporal

47.20 ± 4.32

49.21 ± 2.41

− 1.88 (1.33)

− 4.60, 0.84

1.0000

DRCP, % area

Average

50.86 ± 2.35

51.97 ± 2.39

− 0.99 (0.92)

− 2.88, 0.89

1.0000

Superior

52.32 ± 3.72

53.94 ± 5.66

− 1.85 (1.91)

− 5.75, 2.06

1.0000

Inferior

52.21 ± 3.81

53.46 ± 4.66

− 0.78 (1.67)

− 4.20, 2.63

1.0000

Nasal

49.26 ± 2.82

50.27 ± 2.68

− 0.80 (1.08)

− 3.01, 1.40

1.0000

Temporal

49.63 ± 4.67

50.19 ± 3.93

− 0.53 (1.53)

− 3.67, 2.61

1.0000

RPC, % area

Average

52.32 ± 6.05

61.54 ± 2.38

− 10.54 (1.61)

− 13.83, − 7.26

< 0.0001

Superior

64.19 ± 6.94

71.61 ± 2.82

− 8.69 (1.92)

− 12.62, − 4.76

< 0.0001

Inferior

63.53 ± 8.57

72.42 ± 3.50

− 10.58 (2.36)

− 15.40, − 5.76

0.0015

Nasal

41.48 ± 6.51

50.50 ± 3.47

− 9.87 (1.99)

− 13.94, − 5.80

< 0.0001

Temporal

40.27 ± 6.40

50.90 ± 4.64

− 12.46 (1.89)

− 16.32, − 8.60

< 0.0001

  1. SRCP superficial retinal capillary plexus, DRCP deep retinal capillary plexus, RPC radial peripapillary capillary, SE standard error, CI confidence interval.
  2. Values are shown as mean ± standard deviation.
  3. *P-values were estimated by linear regression analysis with adjustment for age and spherical equivalent refractive errors and Bonferroni correction magnified by 15.
  4. Boldface indicates statistical significance.