Figure 2
From: The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer
Frequency of CCR8+ Tregs is associated with patient prognosis but not tumor stage. (A) Percentages of CCR8+ FOXP3+ cells in CD45+ cells in lung tumors based on clinical stage (n = 50). Statistical significance was determined by one-way ANOVA Kruskal–Wallis test followed by Dunn. (B) Kaplan–Meier analysis of disease-free survival based on the level of CCR8+ Tregs. Lung cancer patients (n = 50) were divided into high and low CCR8+ Treg groups based on the median percentage of CCR8+ FOXP3+/CD45+ cells in TICs. Statistical significance was determined by the log-rank (Mantel–Cox) test.
