Figure 2 | Scientific Reports

Figure 2

From: Characterization of aging tumor microenvironment with drawing implications in predicting the prognosis and immunotherapy response in low-grade gliomas

Figure 2

Classification for LGG samples based on the expression patterns of ATMERS. (a) Consensus clustering for LGG samples identified two clusters. (b) PCA verified the subgroup assignment of LGG samples. (c) C1 exhibited significantly shorter overall survival than C2. (d) The progression free survival for C1 was significantly shorter than C2. (e) Heatmap showing the distinct TME patterns between C1 and C2. (f) Comparisons of immune score, stromal score, ESTIMATE score and tumor purity between C1 and C2. * means p < 0.05, ** means p < 0.01, and ***means p < 0.001. LGG, low-grade glioma; ATMERS, aging tumor microenvironment related signature; PCA, principal component analysis; TME, tumor microenvironment.

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