Figure 6 | Scientific Reports

Figure 6

From: Characterization of aging tumor microenvironment with drawing implications in predicting the prognosis and immunotherapy response in low-grade gliomas

Figure 6

Immunosuppressive phenotype was identified in the TME of the high aging TME score group. (a) Results of the abundance of immune or stromal cells calculated by MCP counter algorithm and immune or stromal scores calculated by ESTIMATE algorithm. (b) The correlation between aging TME score and infiltrated immune cells evaluated by CIBERSORT algorithm. (c) The expression profiles of genes involved in the negative regulation of anti-tumor immune response between low and high aging TME score groups. (d) Differentially expression of the immune suppressive cytokines between the two groups. (e) Differentially expression of the common immune checkpoints between the two groups. (f) Comparisons of TIDE scores between the two groups. * means p < 0.05, ** means p < 0.01, and ***means p < 0.001. TME, tumor microenvironment.

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