Table 4 Simple and multiple linear regression model (estimated value [95% confidence intervals]) for post index date of pneumonia (post-ID pneumonia) periods in chronic rhinosinusitis without nasal polyp compared to control group and subgroup analysis according to age and sex.

From: Association between chronic rhinosinusitis and pneumonia: a longitudinal follow-up study using a national health screening cohort

Characteristics	Mean ± SD in CRS without nasal polyp group	Mean ± SD in control group	Linear regression of CRS without nasal polyp for pneumonia
Characteristics	Mean ± SD in CRS without nasal polyp group	Mean ± SD in control group	Simple^b	P value	Model 1^bc	P value	Model 2^bd	P value
Total participants (n = 15,445)
1-y post-ID pneumonia	0.11 ± 0.85	0.06 ± 0.60	0.051 (0.025 to 0.077)	< 0.001^a	0.025 (− 0.001 to 0.051)	0.056	0.035 (0.010 to 0.060)	0.007^a
2-y post-ID pneumonia	0.09 ± 0.68	0.05 ± 0.59	0.042 (0.018 to 0.066)	0.001^a	0.011 (− 0.013 to 0.035)	0.367	0.017 (− 0.006 to 0.041)	0.155
3-y post-ID pneumonia	0.11 ± 0.80	0.05 ± 0.54	0.059 (0.035 to 0.082)	< 0.001^a	0.033 (0.009 to 0.057)	0.007^a	0.037 (0.014 to 0.061)	0.002^a
Age < 60 years old (n = 9925)
1-y post-ID pneumonia	0.07 ± 0.65	0.03 ± 0.39	0.038 (0.015 to 0.060)	0.001^a	0.021 (− 0.002 to 0.044)	0.068	0.025 (0.003 to 0.047)	0.027^a
2-y post-ID pneumonia	0.06 ± 0.56	0.03 ± 0.38	0.036 (0.016 to 0.057)	0.001^a	0.023 (0.002 to 0.044)	0.030^a	0.026 (0.005 to 0.047)	0.014^a
3-y post-ID pneumonia	0.09 ± 0.77	0.03 ± 0.39	0.054 (0.030 to 0.078)	< 0.001^a	0.035 (0.011 to 0.060)	0.005^a	0.038 (0.013 to 0.062)	0.003^a
Age ≥ 60 years old (n = 5520)
1-y post-ID pneumonia	0.19 ± 1.12	0.11 ± 0.86	0.075 (0.015 to 0.136)	0.014^a	0.039 (− 0.022 to 0.099)	0.212	0.057 (− 0.001 to 0.115)	0.056
2-y post-ID pneumonia	0.15 ± 0.87	0.10 ± 0.84	0.052 (− 0.003 to 0.108)	0.066	− 0.003 (− 0.058 to 0.052)	0.917	0.008 (− 0.046 to 0.063)	0.771
3-y post-ID pneumonia	0.16 ± 0.85	0.09 ± 0.74	0.068 (0.018 to 0.118)	0.008^a	0.035 (− 0.015 to 0.085)	0.174	0.042 (− 0.008 to 0.092)	0.097
Males (n = 8,520)
1-y post-ID pneumonia	0.10 ± 0.72	0.06 ± 0.60	0.035 (0.002 to 0.068)	0.037^a	0.006 (− 0.027 to 0.039)	0.730	0.015 (− 0.017 to 0.047)	0.367
2-y post-ID pneumonia	0.09 ± 0.68	0.06 ± 0.60	0.036 (0.003 to 0.068)	0.032^a	0.001 (− 0.032 to 0.033)	0.958	0.007 (− 0.025 to 0.039)	0.677
3-y post-ID pneumonia	0.12 ± 0.76	0.06 ± 0.59	0.066 (0.033 to 0.099)	< 0.001^a	0.040 (0.007 to 0.073)	0.019^a	0.044 (0.011 to 0.077)	0.010^a
Females (n = 6,925)
1-y post-ID pneumonia	0.13 ± 0.98	0.06 ± 0.60	0.071 (0.030 to 0.112)	0.001^a	0.050 (0.008 to 0.091)	0.019^a	0.060 (0.020 to 0.100)	0.004^a
2-y post-ID pneumonia	0.10 ± 0.69	0.05 ± 0.57	0.050 (0.015 to 0.085)	0.005^a	0.023 (− 0.013 to 0.058)	0.211	0.029 (− 0.006 to 0.064)	0.104
3-y post-ID pneumonia	0.10 ± 0.85	0.05 ± 0.48	0.050 (0.016 to 0.084)	0.004^a	0.024 (− 0.010 to 0.058)	0.163	0.029 (− 0.004 to 0.063)	0.088

CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; DBP, diastolic blood pressure; CRS, chronic rhinosinusitis; 1-y pre-ID pneumonia, pneumonia history from the date of CRS treatment (index date) to the date before 1-year periods; Post-ID pneumonia, the number of pneumonia diagnosis from the index date to the date after certain periods; SBP, systolic blood pressure; SD, standard deviation.
^aLinear regression model, Significance at P < 0.05.
^bModels were stratified by age, sex, income, and region of residence.
^cA model 1 was adjusted for obesity, smoking, alcohol consumption, total cholesterol, SBP, DBP, fasting blood glucose, CCI scores, asthma, and COPD.
^dA model 2 was adjusted for the model 1 plus 1-y pre-ID pneumonia.

Back to article page

Table 4 Simple and multiple linear regression model (estimated value [95% confidence intervals]) for post index date of pneumonia (post-ID pneumonia) periods in chronic rhinosinusitis without nasal polyp compared to control group and subgroup analysis according to age and sex.

Search

Quick links