Figure 2
From: Naturally occurring combinations of receptors from single cell transcriptomics in endothelial cells
Dendrogram analysis identifies naturally occurring combinations of angiogenesis receptors in endothelial cells. The top of panels (A) and (B) displays the dendrogram ordering by single cell co-expression of receptors in endothelial cells for: (A) Mus musculus and (B) Homo sapiens. Receptors that are co-expressed in individual cells are closer to each other in the dendrogram order. Known angiogenesis receptors are labeled under the dendrogram. The red pointer indicates KDR, the main VEGFA receptor. The panels immediately below the dendrogram show three measures: Expression fraction, Network enrichment and Evolutionary conservation. The lowest panel shows the combination of these three measures. The solid orange line in each panel is a moving window average. The largest peak in the combination of measures panel, representing the main comberon (abbreviation for naturally occurring combination) is shown with a red background.
